Copyright © 1997, 2001 by Galen Daryl Knight and VitaleTherapeutics,
Inc.
Articles on Eosinophilia-myalgia and Tryptophan Contaminant
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Silver, R.M., Ludwicka, A., Hampton, M., Ohba, T., Bingel, S.A., Smith,
T., Harley, R.A., Maize, J., and Heyes, M.P. A murine model of the eosinophilia-myalgia
syndrome induced by 1,1'-ethylidenebis(L-tryptophan). J. Clin. Invest.,
93(4): 1473-1480, 1994.
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Yamaoka, K.A., Miyasaka, N., Inuo, G., Saito, I., Kolb, J.-P., Fujita,
K., and Kashiwazaki, S. 1,1'-Ethylidenebis(tryptophan) (Peak E) induces
functional activation of human eosinophils and interleukin 5 production
from T lymphocytes: Association of eosinophilia-myalgia syndrome with a
L-tryptophan contaminant.
J. Clin. Immunol., 14(1): 50-60, 1994.
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Emslie-Smith, A.M., Mayeno, A.N., Nakano, S., Gleich, G.J., and Engel,
A.G. 1,1'-Ethylidenebis[tryptophan] induces pathologic alterations in muscle
similar to those observed in the eosinophilia-myalgia syndrome Neurology,
44(12): 2390-2392, 1994.
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Michelson, D., Page, S.W., Casey, R., Trucksess, M.W., Love, L.A., Milstien,
S., Wilson, C., Massaquoi, S.G., Crofford, L.J., Hallett, M., Gold, P.W.,
and Sternberg, E.M. An eosinophilia myalgia syndrome related disorder associated
with exposure to L-5-hydroxytryptophan. J. Rheumatol., 21(12): 2261-2265,
1994.
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