CONTAMINATED NEEDLESTICK: DEFINITION: "stuck" with a contaminated needle. Most blood-contaminated needlesticks do NOT transmit any disease, however, cautions are necessary. Virtually any viral infection can be transmitted through a needlestick, including several types of hepatitis and AIDS. If the source of the blood is known, that person can be tested for hepatitis and AIDS virus. If you haven't had a Hepatitis B shot, Hepatitis B immune globulin is given if the blood source is positive for hepatitis B. Human serum immune globulin is sometimes given to prevent transmission of other viral diseases. If given, the injection is repeated in 30 days. If you desire AIDS testing, this can be performed initially, then repeated in two months, six months, and one year.